Tendinopathy—from basic science to treatment

Lysyl oxidase: from basic science to future cancer treatment.

In this mini-review, we discuss the physiological and pathological roles of lysyl oxidase (LOX) and its family, LOX-like proteins (LOXL), in relation to prognosis of major cancers. The number of reports on LOX family is numerous. We have decided to review the articles that were recently published (i.e. past 5 years). Experimental techniques in molecular biology have advanced surprisingly in the...

Understanding posterior meniscal roots lesions: from basic science to treatment☆

The variability of symptoms and the fact that they are not easily recognized in imaging studies make the diagnosis and treatment of posterior meniscal roots lesions a challenging task to the orthopedist. In recent years, a more precise understanding of the anatomy and biomechanical impair of the knee joint in these cases has enabled great advances in therapeutic approaches. Well-documented stud...

Basic Facts for Basic Science

Overall, this outstanding text should soon become recognized as the definitive reference for the diagnosis and management of ocular trauma. The tall, narrow shape of Basic Facts for Basic Science suggests that perhaps the author intended that it be put into the pocket of one's lab coat; perhaps not, but this book is certainly appropriate for the shelf of any laboratory and for the office of any...

How basic is basic science?

Some other possible conclusions come easily to mind. Perhaps, if we’re really concerned about students’ learning evidence-based medicine, then we should teach it more or better. On the other hand I am one of many who have joined the anti-EBM movement (Norman 1999). In my view, the fundamental irony remains that, even though it made the BMJ’s ‘‘Top 15 Medical Innovations of all Time’’ list in 20...

Basic Science